PileLine: a toolbox to handle genome position information in next-generation sequencing studies.
作者： Daniel Glez-Peña , Gonzalo Gómez-López , Miguel Reboiro-Jato , Florentino Fdez-Riverola , David G Pisano
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摘要: Background Genomic position (GP) files currently used in next-generation sequencing (NGS) studies are always difficult to manipulate due their huge size and the lack of appropriate tools properly manage them. The structure these flat is based on representing one line per that has been covered by at least aligned read, imposing significant restrictions from a computational performance perspective.
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