High casein-lactalbumin diet accelerates blood coagulation in rats.

摘要: This study investigates the influence of a high protein intake on normal hemostasis, fluid balance and organ growth. Adult rats were fed semipurified diets that contained either 18 or 56 g/100 g casein-lactalbumin for 2 wk, following functions measured: food water intake, weight gain, blood pressure, bleeding clotting time, ADP-stimulated platelet aggregation, thrombin prothrombin time partial thromboplastin time. Although was depressed by diet, gain not affected regimen. Water consumption, 24-h urine excretion kidney significantly greater in diet than controls. High resulted shorter barbiturate-induced sleeping Bleeding lower 7 d. However, heart rate, mean arterial plasma osmolarity, did differ significantly. Because caused rapid coagulation without affecting activity factors, we suggest this sensitized to factors initiate vivo.