摘要: … in cancer by DNA methylation of its promoter and thus a primary target for epigenetic therapy via … miRNA-34b/c is found to be epigenetically silenced in many colon cancer cell lines and …
springer.com
springerlink.com参考文章(44)
T. Jenuwein, Translating the Histone Code Science. ,vol. 293, pp. 1074- 1080 ,(2001) , 10.1126/SCIENCE.1063127
Frank Lyko, Robert Brown, DNA methyltransferase inhibitors and the development of epigenetic cancer therapies. Journal of the National Cancer Institute. ,vol. 97, pp. 1498- 1506 ,(2005) , 10.1093/JNCI/DJI311
B Weber, S Kimhi, G Howard, A Eden, F Lyko, Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription. Oncogene. ,vol. 29, pp. 5775- 5784 ,(2010) , 10.1038/ONC.2010.227
Young-In Kim, Folate and DNA Methylation: A Mechanistic Link between Folate Deficiency and Colorectal Cancer? Cancer Epidemiology, Biomarkers & Prevention. ,vol. 13, pp. 511- 519 ,(2004)
A. Lujambio, G. A. Calin, A. Villanueva, S. Ropero, M. Sanchez-Cespedes, D. Blanco, L. M. Montuenga, S. Rossi, M. S. Nicoloso, W. J. Faller, W. M. Gallagher, S. A. Eccles, C. M. Croce, M. Esteller, A microRNA DNA methylation signature for human cancer metastasis Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 13556- 13561 ,(2008) , 10.1073/PNAS.0803055105
Caifu Chen, Dana A Ridzon, Adam J Broomer, Zhaohui Zhou, Danny H Lee, Julie T Nguyen, Maura Barbisin, Nan Lan Xu, Vikram R Mahuvakar, Mark R Andersen, Kai Qin Lao, Kenneth J Livak, Karl J Guegler, Real-time quantification of microRNAs by stem–loop RT–PCR Nucleic Acids Research. ,vol. 33, pp. 179- ,(2005) , 10.1093/NAR/GNI178
Jean-Pierre J. Issa, Hagop M. Kantarjian, Targeting DNA Methylation Clinical Cancer Research. ,vol. 15, pp. 3938- 3946 ,(2009) , 10.1158/1078-0432.CCR-08-2783
Daniel J Weisenberger, Kimberly D Siegmund, Mihaela Campan, Joanne Young, Tiffany I Long, Mark A Faasse, Gyeong Hoon Kang, Martin Widschwendter, Deborah Weener, Daniel Buchanan, Hoey Koh, Lisa Simms, Melissa Barker, Barbara Leggett, Joan Levine, Myungjin Kim, Amy J French, Stephen N Thibodeau, Jeremy Jass, Robert Haile, Peter W Laird, CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nature Genetics. ,vol. 38, pp. 787- 793 ,(2006) , 10.1038/NG1834
Deepak Kumar, Mukesh Verma, Methods in Cancer Epigenetics and Epidemiology Methods of Molecular Biology. ,vol. 471, pp. 273- 288 ,(2009) , 10.1007/978-1-59745-416-2_14
Guoren Deng, Ada Chen, Erik Pong, Young S Kim, Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression Oncogene. ,vol. 20, pp. 7120- 7127 ,(2001) , 10.1038/SJ.ONC.1204891