Molecular Pathology and Diagnostics of Colorectal Cancer
作者： Rodney E. Shackelford , Aejaz Nasir , Ardeshir Hakam , David Shibata , Timothy Yeatman
DOI: 10.1007/978-94-007-7192-5_5
关键词:
摘要: Colorectal carcinoma (CRC) is the third most common malignancy in United States and second leading cause of cancer deaths. Over past 20 years, our knowledge this CRC carcinogenesis has enormously increased; presently, several molecular diagnostic tests are commonly employed to analyze stage IV familiar syndromes determine treatment options inheritance risk. More recently number expanded as increased. Here, we review standard CRC, such KRAS Braf analyses, also include less related microsatellite instability. Last, focus on possible future genetic testing modalities, focusing techniques microarray mass spectrophotometry.
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