C-terminally truncated dengue and Japanese encephalitis virus envelope proteins

作者: Ching-Jun Lai , Lei-Ron Jan , Ruhe Men , Michael Bray

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摘要: The present invention relates to C-terminally truncated flavivirus envelope proteins 80-81% in size which are more immunogenic than their counterpart full-length proteins. further recombinant viruses encode the protein and host cells infected therewith. Host express on outer membrane secrete it into medium. vaccines for use against infection. include either a vaccinia virus expressing of invention, produced by baculovinis.

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