Selectivity properties of poly-N-vinyl pyrrolidone in column chromatography of nucleotides, their derivatives, and related compounds: a preliminary report.

作者: Joseph Lerner , Therese M. Dougherty , Abner I. Schepartz

DOI: 10.1016/S0021-9673(01)99140-X

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摘要: Abstract Insoluble poly-N-vinyl pyrrolidone (PVP) has been found to possess selectivity properties toward various nucleotide derivatives and can be used for column chromatography employing water as eluent. Compounds emerge from the columns in this order: nucleotides, pyrimidines, purines. Total elution volumes times series of compounds investigated are 45 ml (5 h) with use a 0.9 x 22.3 cm 20 (65 min) 10.8 column.

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