Cellular and humoral immunity in non-Hodgkin's lymphoma: correlation of immunodeficiencies with clinicopathologic factors.

摘要: Immune function was evaluated in 28 non-Hodgkin's lymphoma patients an attempt to correlate the occurrence of immunodeficiency with prognostic clinicopathologic factors, lymph-node histology, and clinical stage disease. Anergy a battery recall antigens occurred infrequently (4/28) only who had Stage IV disease (4/8) (p = less than .004), but did not histology. In contrast anergy, cellular immunodeficiencies were often detected by lack response keyhole limpet hemocyanin immunization regardless stage. Reductions at least two three Ig fractions found third patients, with, again, significantly greater incidence .005). No significant correlation histologic type possible. The phytohemagglutinin vitro reduced this no correlative value.