作者: C. Ruiz , G. Hernandez , C. Ince
DOI: 10.1007/978-1-4419-5562-3_2
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摘要: Shock has typically been classified into four types: Hypovolemic, cardiogenic, obstructive, and distributive. The first three categories are associated with a decrease in cardiac output, leading to tissue hypoxia. Distributive shock, such as septic results from abnormal distribution of normal or increased secondary microcirculatory dysfunction. Severe disruption the microcirculation during sepsis pathologic heterogeneity microvascular blood flow that occurs consequence shutdown weak units. This implies oxygen transport is shunted arterial venous compartment, leaving hypoxic, main pathogenic feature distributive shock. Such scenario maldistribution mismatch between delivery demand different tissues seems be step progression organ failure [1].