Discoid lupus erythematosus-like eruption induced by infliximab
作者： A. J. Stratigos , C. Antoniou , S. Stamathioudaki , G. Avgerinou , A. Tsega
DOI: 10.1111/J.1365-2230.2004.01471.X
关键词:
摘要: Summary Lupus erythematosus-like syndromes have been reported as an adverse effect of anti-tumour necrosis factor-α therapy. We report the case a patient with rheumatoid arthritis who developed discoid lupus eruption after treatment infliximab. The rash consisted diffuse scaly erythematous plaques on face, trunk and extremities, occurred in context elevated anti-nuclear anti-double-stranded DNA antibody titres. Direct immunofluorescence lesional skin showed linear deposition IgG, IgM C3. lesions resolved completely discontinuation infliximab use anti-malarial discuss clinical, histological immunohistochemical features this review literature respect to incidence patients receiving tumour antagonists.
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