Functional Analysis of the Mouse Scn8a Sodium Channel
作者： Marianne R. Smith , Raymond D. Smith , Nicholas W. Plummer , Miriam H. Meisler , Alan L. Goldin
DOI: 10.1523/JNEUROSCI.18-16-06093.1998
关键词:
摘要: The mouse Scn8a sodium channel and its ortholog Na6 in the rat are abundantly expressed in the CNS. Mutations in mouse Scn8a result in neurological disorders, including paralysis, …
core.ac.uk
sci-hub.se 参考文章(35)
S. Beckh, M. Noda, H. Lübbert, S. Numa, Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development The EMBO Journal. ,vol. 8, pp. 3611- 3616 ,(1989) , 10.1002/J.1460-2075.1989.TB08534.X
Alan L. Goldin, Chapter 25 Expression of Ion Channels by Injection of mRNA into Xenopus Oocytes Methods in Cell Biology. ,vol. 36, pp. 487- 509 ,(1991) , 10.1016/S0091-679X(08)60293-9
Indira M. Raman, Bruce P. Bean, Resurgent Sodium Current and Action Potential Formation in Dissociated Cerebellar Purkinje Neurons The Journal of Neuroscience. ,vol. 17, pp. 4517- 4526 ,(1997) , 10.1523/JNEUROSCI.17-12-04517.1997
KL Schaller, DM Krzemien, NM McKenna, JH Caldwell, Alternatively spliced sodium channel transcripts in brain and muscle. The Journal of Neuroscience. ,vol. 12, pp. 1370- 1381 ,(1992) , 10.1523/JNEUROSCI.12-04-01370.1992
KL Schaller, DM Krzemien, PJ Yarowsky, BK Krueger, JH Caldwell, A novel, abundant sodium channel expressed in neurons and glia The Journal of Neuroscience. ,vol. 15, pp. 3231- 3242 ,(1995) , 10.1523/JNEUROSCI.15-05-03231.1995
W. A. Catterall, Cellular and molecular biology of voltage-gated sodium channels. Physiological Reviews. ,vol. 72, ,(1992) , 10.1152/PHYSREV.1992.72.SUPPL_4.S15
Kelly D. Garcı́a, Leslie K. Sprunger, Miriam H. Meisler, Kurt G. Beam, The Sodium Channel Scn8a Is the Major Contributor to the Postnatal Developmental Increase of Sodium Current Density in Spinal Motoneurons The Journal of Neuroscience. ,vol. 18, pp. 5234- 5239 ,(1998) , 10.1523/JNEUROSCI.18-14-05234.1998
R. J. BOAKES, J. B. HARRIS, D.K. DICK, A cerebellar abnormality in the mouse with motor end-plate disease. Neuropathology and Applied Neurobiology. ,vol. 11, pp. 141- 147 ,(1985) , 10.1111/J.1365-2990.1985.TB00011.X
J.B. Harris, R.J. Boakes, J.A. Court, Physiological and biochemical studies on the cerebellar cortex of the murine mutants “jolting” and “motor end-plate disease” Journal of the Neurological Sciences. ,vol. 110, pp. 186- 194 ,(1992) , 10.1016/0022-510X(92)90027-I
L. Isom, K. De Jongh, D. Patton, B. Reber, J Offord, H Charbonneau, K Walsh, A. Goldin, W. Catterall, Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel Science. ,vol. 256, pp. 839- 842 ,(1992) , 10.1126/SCIENCE.1375395