Genotyping of 75 SNPs using arrays for individual identification in five population groups.

摘要: Single nucleotide polymorphism (SNP) typing offers promise to forensic genetics. Various strategies and panels for analyzing SNP markers individual identification have been published. However, the best with fewer identity SNPs all major population groups are still under discussion. This study aimed find more autosomal high heterozygosity among Asian populations. Ninety-six of 502 DNA samples from unrelated individuals five (208 Taiwanese Han, 83 Filipinos, 62 Thais, 69 Indonesians, 80 European, Near Eastern, or South ancestry) were analyzed using arrays in an initial screening, 75 (group A, 46 newly selected SNPs; B, 29 based on a previous panel) further statistical analyses. Some populations identified. The combined random match probability 40 45 was between 3.16 × 10−17 7.75 × 10−17 2.33 × 10−19 7.00 × 10−19, respectively, These loci offer comparable power short tandem repeats (STRs) routine profiling. In this study, we demonstrated genetic characteristics parameters groups. panel can provide valuable genotypic information be helpful casework these