Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.
作者： Eric S. Goetzman , Sivakama S. Bharathi , Yuxun Zhang , Xue-Jun Zhao , Steven F. Dobrowolski
DOI: 10.1038/S41598-020-75615-3
关键词:
摘要: … either 100 µM of the irreversible Cpt1 inhibitor etomoxir or 2 mM … MCAD; C 12 -CoA, which is primarily metabolized by LCAD … We postulate that decreased activity of ACSL1, but normal …
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