Combination of anti-CTLA4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases

作者: Maria Jure-Kunkel , Francis Y. Lee

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摘要: A method for the treatment of cancer, comprising administration to a mammal in need thereof synergistic, therapeutically effective amount (i) an anti-CTLA-4 antibody, addition one or more diluents, vehicles, excipients, and/or inactive ingredients, and (ii) N (2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)- 1 -piperazinyl]-2-methyl-4pyrimidinyl] amino] -5-thiazolecarboxamide (dasatinib), pharmaceutically acceptable salt, solvate, hydrate thereof, ingredients.

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