Increase of unesterified fatty acids, prostaglandin F2α but not thromboxane B2 in rat brain during drug induced convulsions
作者： J. Marion , L.S. Wolfe
DOI: 10.1016/0090-6980(78)90206-X
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摘要: Abstract The amount of free arachidonic acid and prostaglandin F 2α in rat cerebral hemispheres was increased following convulsions induced by carbachol metrazol. level thromboxane B 2 not affected endoperoxides could only be “trapped” after a very short convulsive period. Unesterified fatty levels at minutes post-mortem were decreased 50% the phenytoin treated rats. Under same conditions, phenobarbital diazepam had little effect on acids brain.
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