Functionality of the immune system in patients with chronic hepatitis C: trial by superinfections and vaccinations.

摘要: Viral infections, specifically chronic, markedly influence the host response to subsequent infections and vaccinations. Does this apply chronic hepatitis C (CHC)? The review considers question with implications for immune status functionality of system a chronically HCV-infected host. data collected here indicate that CHC may increase risk viral superinfections modify their course by immunocompromising Patients do not lose ‘memory’ previous vaccinations but, apparently, have problems building such immunity anew, as illustrated impaired A B This underlines necessity extra protection patients against blood-borne diseases, A, possibly also varicella, influenza, tetanus, diphtheria – which, in Western population, appears falter. Such has be adapted selective impairments characteristi...