Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
作者： Vishnumurthy Kodumuru , Natalia Pokrovskaia , Serguei Sviridov , Zaihui Zhang , Shaoyi Sun
DOI:
关键词:
摘要: PROBLEM TO BE SOLVED: To provide a method of treating stearoyl-CoA desaturase (SCD)-mediated disease or condition in mammal.SOLUTION: The the mammal, preferably human, comprises step administering to mammal need thereof compound formula (I). In formula, V, W, R, Rand Rare defined specification. Pharmaceutical compositions comprising (I) are also disclosed. includes metabolic syndrome, Syndrome X, diabetes, insulin resistance, decreased glucose tolerance, non-insulin-dependent diabetes mellitus, Type II I diabetic complications, body weight disorders, loss, mass index and leptin related diseases.
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