Regional Cerebral Blood Flow in Mood Disorders, III

摘要: Background: Global and regional deficits in cerebral blood flow glucose metabolism have been reported major depression, but there is limited information on the effects of somatic treatment clinical recovery these abnormalities. Methods: We assessed cortical with xenon 133 technique depressed patients prior to a course electroconvulsive therapy (ECT), 30 minutes before 50 after single treatment, during week following ECT. Acute (preictal postictal) also were studied manic patients. Results: In groups, larger reductions acute period, both globally particular patterns brain regions, associated superior outcome course. patients, similar observed for changes over full Blood anterior regions strongly positive response depression mania. Conclusions: The findings indicated that abnormalities not reversed by successful Rather, particularly responders, ECT resulted additional perfusion reductions. therapeutic properties are related reduced functional activity specific neural regions.