摘要: conta com a cola-boracao de renomados autores que expoem os aspectos considerados relevantes pela Organizacao Pan-Ameri-cana da Saude (OPAS) para recomendar introducao novas vacinas nos programas dos paises membros. Dentre eles, merecem destaque: carga das doencas, caracteristicas e seu impacto sobre pro-gramas, percepcao risco, analise farmaco-economi-ca intervencao, compromisso respaldo politico, aliancas sustentabilidade.Nas ultimas decadas, foram surpreendentes avancos possibilitaram criacao recursos diagnosticos identificar doencas an-tes nao reconhecidas formas atipicas bem conhecidas, aumentando desafios incorporar as contra estas calendarios vaci-nais
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