Anti-proliferative phytoconstituents from Striga angustifolia (D. Don) C.J. Saldanha – An in vitro and in silico approach

摘要: Abstract Background : Striga angustifolia (D.Don) C.J. Saldanha, belonging to the Orabanchaceae, is indicated have notable beneficial properties in traditional medicinal system of Africa. It said that it aids cure several diseases. Therefore, we aimed characterize chemical composition plant by analyzing volatile compounds through GC-MS. The screened were then tested for anticancer activity structure-based models. Purpose present study focus screen whole S. its essential phytoconstituents, vitro and silico anti-proliferative effects. Methods Plant metabolites was profiled tried explore anti-cancer potential using both biochemical models from extracts. Support regression techniques used strengthening investigation. Results ethyl acetate extract showed maximum antioxidant further analysis revealed significant compound 1,5-naphthalenediol. morphological changes high efficiency arresting proliferation cancer cells. Conclusion This helps identifying distinct biomolecules extracts at an early stage. will aid separation molecules a short span time. Thus, eliminating need prolonged experimental trials.