作者: Jean-Christophe Lucet
DOI: 10.1001/ARCHINTERNMED.2009.217
关键词:
摘要: Background Several studies have documented prolonged colonization with hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) after hospital discharge. However, information is lacking about factors associated MRSA and transmission to household contacts. Methods From February 2003 March 2004, adult inpatients (except obstetric patients) were screened for carriage before discharge home health care. Bivariate multivariate analyses performed evaluate rates risk of at discharge, clearance within 1 year, Results We identified in 191 the 1501 patients care (12.7%). Of 148 who observed, 75 cleared organism an estimated median time 282 days (95% confidence interval [CI], 233-313 days). Clearance was self-sufficiency daily activities (hazard ratio, 0.63; 95% CI, 0.40-1.00) ( P = .049). 188 included contacts, 36 acquired (19.1%). Factors acquisition older age (adjusted odds 1.71 per life decade; 1.32-2.21) = .001) participation index patient 3.58; 1.33-9.62) = .01). Conclusions Hospital-acquired common frequently prolonged. Transmission occurred nearly 20% contacts patient. Household should apply infection control measures similar those recommended setting.