作者: Marisa Assunção , Dorsa Dehghan-Baniani , Chi Him Kendrick Yiu , Thomas Später , Sebastian Beyer
DOI: 10.3389/FBIOE.2020.602009
关键词:
摘要: Cell-derived extracellular matrices (CD-ECMs) captured increasing attention since the first studies in the 1980s. The biological resemblance of CD-ECMs to their in vivo counterparts and natural complexity provide them with a prevailing bioactivity. CD-ECMs offer the opportunity to produce microenvironments with costumizable biological and biophysical properties in a controlled setting. As a result, CD-ECMs can improve cellular functions such as stemness or be employed as a platform to study cellular niches in health and disease …