Gastroesophageal reflux in children with cerebral palsy: efficacy of cisapride.

摘要: The aim of this study was to investigate the presence gastroesophageal reflux with 24-hour pH monitoring in children cerebral palsy. In second part study, we started cisapride documented and evaluated efficacy monitoring. This performed before discontinuation US Food Drug Administration reports Turkish markets. Twenty-eight who had been followed up Department Pediatric Neurology between 1999 2000 were enrolled study. Twenty-four-hour on all patients. Two parameters as pathologic: a index (percentage time value or =4.5% 13 (46.4%) 28 cases. Reflux longer than 15 minutes 2 (7.1%) Cisapride cases pathologic results. Appetite improved 6 dysphagia disappeared 8 after therapy (P < .05). repeated 12 3 months normal them. Improvement total episodes statistically significant = .008). No adverse effects occurred. Even though drug is no marketed, concluded that it symptoms quality life spastic reflux.