Saturated Fatty Acids Promote Endoplasmic Reticulum Stress and Liver Injury in Rats with Hepatic Steatosis

作者: Dong Wang , Yuren Wei , Michael J. Pagliassotti

DOI: 10.1210/EN.2005-0570

关键词:

摘要: Nonalcoholic fatty liver disease is a relatively new hepatic sequela of obesity and type 2 diabetes. The pathogenesis of liver injury and disease progression in nonalcoholic fatty liver …

参考文章(57)
Bao-Hong Zhang, Martin Weltman, Geoffrey Farrell, Does steatohepatitis impair liver regeneration? A study in a dietary model of non-alcoholic steatohepatitis in rats Journal of Gastroenterology and Hepatology. ,vol. 14, pp. 133- 137 ,(2002) , 10.1046/J.1440-1746.1999.01822.X
Bruce N. Ames, Donald T. Dubin, The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. Journal of Biological Chemistry. ,vol. 235, pp. 769- 775 ,(1960) , 10.1016/S0021-9258(19)67936-6
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
Michael E. Bizeau, Chiffon Short, Jeffrey S. Thresher, S. Renee Commerford, Wayne T. Willis, Michael J. Pagliassotti, Increased pyruvate flux capacities account for diet-induced increases in gluconeogenesis in vitro American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 281, ,(2001) , 10.1152/AJPREGU.2001.281.2.R427
M. J. Pagliassotti, P. A. Prach, T. A. Koppenhafer, D. A. Pan, Changes in insulin action, triglycerides, and lipid composition during sucrose feeding in rats American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 271, ,(1996) , 10.1152/AJPREGU.1996.271.5.R1319
Michael J. Pagliassotti, Yuren Wei, Michael E. Bizeau, Glucose-6-Phosphatase Activity Is Not Suppressed but the mRNA Level Is Increased by a Sucrose-Enriched Meal in Rats Journal of Nutrition. ,vol. 133, pp. 32- 37 ,(2003) , 10.1093/JN/133.1.32
Ping Hu, Zhang Han, Anthony D. Couvillon, John H. Exton, Critical Role of Endogenous Akt/IAPs and MEK1/ERK Pathways in Counteracting Endoplasmic Reticulum Stress-induced Cell Death Journal of Biological Chemistry. ,vol. 279, pp. 49420- 49429 ,(2004) , 10.1074/JBC.M407700200
Jeanne M. Clark, Anna Mae Diehl, Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis. JAMA. ,vol. 289, pp. 3000- 3004 ,(2003) , 10.1001/JAMA.289.22.3000
Michael B. Paumen, Yasumasa Ishida, Masamichi Muramatsu, Masaharu Yamamoto, Tasuku Honjo, Inhibition of Carnitine Palmitoyltransferase I Augments Sphingolipid Synthesis and Palmitate-induced Apoptosis Journal of Biological Chemistry. ,vol. 272, pp. 3324- 3329 ,(1997) , 10.1074/JBC.272.6.3324