Hypochlorous Acid-Induced Base Modifications in Isolated Calf Thymus DNA

作者: Matthew Whiteman , Andrew Jenner , Barry Halliwell

DOI: 10.1021/TX970086I

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摘要: Exposure of calf thymus DNA to hypochlorous acid/hypochlorite leads extensive base modification. Large concentration-dependent increases in pyrimidine oxidation products [thymine glycol (cis...

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