Development of axially chiral bis(arylthiourea)-based organocatalysts and their application in the enantioselective Henry reaction

作者: Xu-Guang Liu , Jia-Jun Jiang , Min Shi

DOI: 10.1016/J.TETASY.2007.11.008

关键词:

摘要: Abstract Axially chiral bis(arylthiourea)-based organocatalyst 6b , prepared from ( R )-(+)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl-2,2′-diamine, was found to be an effective for the enantioselective Henry reaction of arylaldehydes with nitromethane give corresponding adducts in moderate enantioselectivities and good yields.

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