Dissimilarities between the central control of thirst and the release of antidiuretic hormone (ADH).

作者: B. Andersson , K. Olsson , R. G. Warner

DOI: 10.1111/J.1748-1716.1967.TB03709.X

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摘要: Effects of slow (7.5 μu1/min) infusions certain hypertonic solutions into the 3rd brain ventricle were studied in 4 unanesthetized goats. The only found to elicit drinking NaCl (0.85 M) and a minor degree) NaHCO3 M). Other tested M Na-acetate NH4Cl, 1.7 urea d-glucose) negative this respect. During 1 hr strong cumulative response was obtained all animals within 3 8 min after start infusion. No occurred when hydrated prior effects on water diuresis short (2 10 min) periods infusion same goats previous hydration. In 2 sodium salts NH4Cl caused an inhibition neurohypophysial type, paralleling effect i.v. injection approximately mU ADH. A considerably smaller by no seen due d-glucose. one from either or NH4Cl. animal site more posterior ventral than responding animals.

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