作者: Zhanpeng Zhang , Melanie J Gupte , Peter X Ma
DOI: 10.1517/14712598.2013.756468
关键词:
摘要: Introduction: Organ failure and tissue loss are challenging health issues due to widespread injury, the lack of organs for transplantation limitations conventional artificial implants. The field engineering aims provide alternative living substitutes that restore, maintain or improve function. Areas covered: In this paper, a wide range porous scaffolds reviewed, with an emphasis on phase-separation techniques generate advantageous nanofibrous 3D stem cell-based applications. addition, methods presentation delivery bioactive molecules mimic properties cell niches summarized. Recent progress in using these bioinstructive support differentiation regeneration is also presented. Expert opinion: Stem cells have great clinical potential because their capability differentiate into multiple types. Biomaterials served as extracellular environments r...