Carbon monoxide from CORM-2 reduces HMGB1 release through regulation of IFN-β/JAK2/STAT-1/INOS/NO signaling but not COX-2 in TLR-activated macrophages.
作者： Konstantin Tsoyi , Irina Tsoy Nizamutdinova , Hwa Jin Jang , Lidiya Mun , Hye Jung Kim
DOI: 10.1097/SHK.0B013E3181E46F15
关键词:
摘要: … Recently, we found that carbon monoxide (CO… Carbon monoxide-releasing molecule 2 (CORM-2) specifically inhibited the expression of iNOS (NO), but not of cyclooxygenase 2 (COX-2…
lww.com
sci-hub.se 参考文章(33)
Mariarosaria Bucci, Jean-Philippe Gratton, Radu Daniel Rudic, Lisette Acevedo, Fiorentina Roviezzo, Giuseppe Cirino, William C Sessa, None, In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation Nature Medicine. ,vol. 6, pp. 1362- 1367 ,(2000) , 10.1038/82176
Ju-Hyun Kim, Seon-Ju Kim, Im-Soon Lee, Myung-Shik Lee, Satoshi Uematsu, Shizuo Akira, Kwon Ik Oh, None, Bacterial Endotoxin Induces the Release of High Mobility Group Box 1 via the IFN-β Signaling Pathway Journal of Immunology. ,vol. 182, pp. 2458- 2466 ,(2009) , 10.4049/JIMMUNOL.0801364
Leo E Otterbein, Fritz H Bach, Jawed Alam, Miguel Soares, Hong Tao Lu, Mark Wysk, Roger J Davis, Richard A Flavell, Augustine MK Choi, None, Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway Nature Medicine. ,vol. 6, pp. 422- 428 ,(2000) , 10.1038/74680
Xiao Mei Wang, Hong Pyo Kim, Kiichi Nakahira, Stefan W. Ryter, Augustine M. K. Choi, The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1. Journal of Immunology. ,vol. 182, pp. 3809- 3818 ,(2009) , 10.4049/JIMMUNOL.0712437
Sean Garrean, Xiao-Pei Gao, Victor Brovkovych, Jun Shimizu, You-Yang Zhao, Stephen M. Vogel, Asrar B. Malik, Caveolin-1 Regulates NF-κB Activation and Lung Inflammatory Response to Sepsis Induced by Lipopolysaccharide Journal of Immunology. ,vol. 177, pp. 4853- 4860 ,(2006) , 10.4049/JIMMUNOL.177.7.4853
Salvador Moncada, Nitric oxide: discovery and impact on clinical medicine: Journal of the Royal Society of Medicine. ,vol. 92, pp. 164- 169 ,(1999) , 10.1177/014107689909200402
Sarah L. Doyle, Luke A.J. O’Neill, Toll-like receptors: From the discovery of NFκB to new insights into transcriptional regulations in innate immunity Biochemical Pharmacology. ,vol. 72, pp. 1102- 1113 ,(2006) , 10.1016/J.BCP.2006.07.010
Outi Sareila, Riku Korhonen, Outi Kärpänniemi, Riina Nieminen, Hannu Kankaanranta, Eeva Moilanen, Janus kinase 3 inhibitor WHI-P154 in macrophages activated by bacterial endotoxin: Differential effects on the expression of iNOS, COX-2 and TNF-α International Immunopharmacology. ,vol. 8, pp. 100- 108 ,(2008) , 10.1016/J.INTIMP.2007.10.016
Man Yu, Haichao Wang, Aihao Ding, Douglas T. Golenbock, Eicke Latz, Christopher J. Czura, Matthew J. Fenton, Kevin J. Tracey, Huan Yang, HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock. ,vol. 26, pp. 174- 179 ,(2006) , 10.1097/01.SHK.0000225404.51320.82
Tadashi Tanabe, Norimitsu Tohnai, Cyclooxygenase isozymes and their gene structures and expression Prostaglandins & Other Lipid Mediators. ,vol. 68-69, pp. 95- 114 ,(2002) , 10.1016/S0090-6980(02)00024-2