AUTOIMMUNHEPATITIS, AUTOIMMUNGASTRITIS, HYPERGASTRINAMIE UND MAGENKARZINOIDE

摘要: A 48-year-old woman with type II diabetes developed fatigue, arthralgia and myalgia. few weeks later she was found to have hepatomegaly. The erythrocyte sedimentation rate raised (53/93 mm), as were liver enzyme activities (GOT 186 U/l; GPT 240 gamma-GT 199 U/l), the gamma-globulin levels (40.7%;IgG 4470 mg/dl, IgA 698 IgM 245 mg/dl), antinuclear antibodies against double-strand DNA, smooth muscles actin. Laparoscopy revealed small-nodular cirrhosis. autoimmune hepatitis treated prednisolone (initially 60 mg daily, then reduced 10 daily) azathioprine 100 50 daily). symptoms markedly improved. But one year later, during follow-up examination, gastric polyps found, excised histologically be carcinoid. gastrin level 765 pg/ml. Another cirrhosis had advanced further gastritis still present, but there no sign of carcinoid recurrence.