Subtle consequences of methylmercury exposure, behavioral deviations in offspring of treated mothers.
作者： J. M. Spyker , S. B. Sparber , A. M. Goldberg
DOI: 10.1126/SCIENCE.177.4049.621
关键词:
摘要: Overt neurological impairment is the endpoint currently used to document a case of methylmercury poisoning. No consideration given possible subtle consequences. Offspring from mice exposed on day 7 or 9 pregnancy were apparently unaffected during postnatal development. However, behavioral differences between treated and control offspring found when overtly normal animals tested in an open field evaluated swimming apparatus at 1 month age. Brain weight, protein, choline acetyltransferase, cholinesterase not significantly altered.
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