Ecology of Antibiotic Resistance Genes

作者: Abigail A. Salyers , Hera Vlamakis , Nadja B. Shoemaker

DOI: 10.1128/9781555817572.CH33

关键词:

摘要: This chapter starts with a brief history of the growing public interest in ecology resistance genes and then moves on to survey some conceptual problems that have emerged. It focuses few groups bacteria are major players oral intestinal ecosystems humans animals, obligate anaerobes. Perhaps first modern example sudden importance understanding antibiotic arose connection debate over safety GM plants. Studies shown many soil naturally transformable, although it is still unclear what significance this fact has overall genes. Bacteria human body participated distribution An interesting case point population makes its home periodontal pocket, region between gums roots teeth. Prominent among these Porphyromonas Prevotella species. These been particular dentistry because they thought be instrumental development disease, main cause tooth loss adults. Currently, treatment for disease surgery cuts into gums, exposing buried surface teeth allow scraping plaque accumulated there causing inflammation.

参考文章(96)
N B Shoemaker, G R Wang, A A Salyers, Evidence for natural transfer of a tetracycline resistance gene between bacteria from the human colon and bacteria from the bovine rumen. Applied and Environmental Microbiology. ,vol. 58, pp. 1313- 1320 ,(1992) , 10.1128/AEM.58.4.1313-1320.1992
R E Lenski, S C Simpson, T T Nguyen, Genetic analysis of a plasmid-encoded, host genotype-specific enhancement of bacterial fitness. Journal of Bacteriology. ,vol. 176, pp. 3140- 3147 ,(1994) , 10.1128/JB.176.11.3140-3147.1994
M P Nikolich, G Hong, N B Shoemaker, A A Salyers, Evidence for natural horizontal transfer of tetQ between bacteria that normally colonize humans and bacteria that normally colonize livestock Applied and Environmental Microbiology. ,vol. 60, pp. 3255- 3260 ,(1994) , 10.1128/AEM.60.9.3255-3260.1994
Tae-Young Ahn, Jung-Gyu Kang, Seong Hwan Kim, Bacterial diversity in the human saliva from different ages. Journal of Microbiology. ,vol. 44, pp. 572- 576 ,(2006)
W. E. C. Moore, Lillian V. Holdeman, Human Fecal Flora: The Normal Flora of 20 Japanese-Hawaiians Applied Microbiology. ,vol. 27, pp. 961- 979 ,(1974) , 10.1128/AM.27.5.961-979.1974
M P Nikolich, N B Shoemaker, G R Wang, A A Salyers, Characterization of a new type of Bacteroides conjugative transposon, Tcr Emr 7853. Journal of Bacteriology. ,vol. 176, pp. 6606- 6612 ,(1994) , 10.1128/JB.176.21.6606-6612.1994
Laura M. McMurry, Margret Oethinger, Stuart B. Levy, Triclosan targets lipid synthesis Nature. ,vol. 394, pp. 531- 532 ,(1998) , 10.1038/28970