Controversial cytogenetic observations in mammalian somatic cells exposed to extremely low frequency electromagnetic radiation: a review and future research recommendations.

作者: Vijayalaxmi , Guenter Obe

DOI: 10.1002/BEM.20111

关键词:

摘要: During the years 1990-2003, a large number of investigations were conducted using animals, cultured rodent and human cells as well freshly collected blood lymphocytes to determine genotoxic potential exposure nonionizing radiation emitted from extremely low frequency electromagnetic fields (EMF). Among 63 peer reviewed scientific reports, conclusions 29 studies (46%) did not indicate increased damage genetic material, assessed DNA strand breaks, incidence chromosomal aberrations (CA), micronuclei (MN), sister chromatid exchanges (SCE), in EMF exposed compared with sham and/or unexposed cells, while those 14 (22%) have suggested an increase such cells. The observations 20 other (32%) inconclusive. This study reviews published journals during 1990-2003 attempts identify probable reason(s) for conflicting results. Recommendations are made future research address some controversial observations.

参考文章(79)
David Scott, Sheila M. Galloway, Richard R. Marshall, Motoi Ishidate, David Brusick, John Ashby, Brian C. Myhr, Genotoxicity under extreme culture conditions. A report from ICPEMC task group 9 Mutation Research\/reviews in Genetic Toxicology. ,vol. 257, pp. 147- 205 ,(1991) , 10.1016/0165-1110(91)90024-P
Olga Zeni, Ferdinando Bersani, Maria Scarfì, Radiological workers sensitivity to 50 Hz pulsed magnetic fields: preliminary results. Radiation and Environmental Biophysics. ,vol. 41, pp. 275- 279 ,(2002) , 10.1007/S00411-002-0170-7
L Ellam, J Pippard, Electroconvulsion treatment in Great Britain 1980. The Lancet. ,vol. 2, pp. 1160- 1161 ,(1981)
Samuel Monroe Cohen, Leon B. Ellwein, Genetic errors, cell proliferation, and carcinogenesis Cancer Research. ,vol. 51, pp. 6493- 6505 ,(1991)
Y.R. Ahuja, A. Bhargava, S. Sircar, W. Rizwani, S. Lima, A.H. Devadas, S.C. Bhargava, Comet assay to evaluate DNA damage caused by magnetic fields international conference on electromagnetic interference and compatibility. pp. 273- 276 ,(1997) , 10.1109/ICEMIC.1997.669812
B M Svedenstal, M O Mattsson, K J Johanson, L E Paulsson, DNA damage, cell kinetics and ODC activities studied in CBA mice exposed to electromagnetic fields generated by transmission lines. in Vivo. ,vol. 13, pp. 507- 513 ,(1999)
Giovannino Ciccone, Dario Mirabelli, Alessandro Levis, Paolo Gavarotti, Giovanna Rege-Cambrin, Laura Davico, Paolo Vineis, Myeloid leukemias and myelodysplastic syndromes: chemical exposure, histologic subtype and cytogenetics in a case-control study Cancer Genetics and Cytogenetics. ,vol. 68, pp. 135- 139 ,(1993) , 10.1016/0165-4608(93)90010-J
J.P McNamee, P.V Bellier, J.R.N McLean, L Marro, G.B Gajda, A Thansandote, DNA damage and apoptosis in the immature mouse cerebellum after acute exposure to a 1 mT, 60 Hz magnetic field Mutation Research-genetic Toxicology and Environmental Mutagenesis. ,vol. 513, pp. 121- 133 ,(2002) , 10.1016/S1383-5718(01)00302-3
Gordon K. Livingston, Kristine L. Witt, Om P. Gandhi, Indira Chatterjee, Joseph L. Roti Roti, L. G. Littlefield, Reproductive integrity of mammalian cells exposed to power frequency electromagnetic fields Environmental and Molecular Mutagenesis. ,vol. 17, pp. 49- 58 ,(1991) , 10.1002/EM.2850170108