Characterisation of a cobalt-60 small-beam animal irradiator using a realtime silicon pixelated detector

作者: C.S. Porumb , J.B. Davies , V. Perevertaylo , A.B. Rosenfeld , M. Petasecca

DOI: 10.1088/1748-0221/11/04/P04014

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摘要: The paper presents a study performed by the Centre for Medical Radiation Physics (CMRP) using high spatial and temporal resolution silicon pixelated detector named MagicPlate-512. focuses on characterisation of three pencil beams from low-dose rate, 6 TBq, cobalt-60 source, in terms percentage depth dose, beam profiles, output factor shutter timing. Where applicable, findings were verified against radiochromic EBT3 film ionization chambers. It was found that results MagicPlate-512 agreed within 0.9 mm penumbra full-width at half-maximum measurements 0.75% dose study. rate source determined to be (10.65 ± 0.03) cGy/min 1.5 cm Solid Water. A significant asymmetry small profile found, which is due irregular machining collimator. average speed calculated 26 cm/s. demonstrates dosimetry system, developed CMRP, capable even cases very low sources.

参考文章(10)
Benjamin J. Blyth, Shizuko Kakinuma, Masaaki Sunaoshi, Yoshiko Amasaki, Shinobu Hirano-Sakairi, Kanae Ogawa, Ayana Shirakami, Yi Shang, Chizuru Tsuruoka, Mayumi Nishimura, Yoshiya Shimada, Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy PLOS ONE. ,vol. 10, pp. e0130666- ,(2015) , 10.1371/JOURNAL.PONE.0130666
Tianwei Zhang, Lin Zhang, Shuqiong Fan, Meizhuo Zhang, Haihua Fu, Yuanjie Liu, Xiaolu Yin, Hao Chen, Liang Xie, Jingchuan Zhang, Paul R. Gavine, Yi Gu, Xingzhi Ni, Xinying Su, Patient-Derived Gastric Carcinoma Xenograft Mouse Models Faithfully Represent Human Tumor Molecular Diversity PLOS ONE. ,vol. 10, pp. e0134493- ,(2015) , 10.1371/JOURNAL.PONE.0134493
Hae Young Yoo, Amy Zeifman, Eun A. Ko, Kimberly A. Smith, Jiwang Chen, Roberto F. Machado, You-Yang Zhao, Richard D. Minshall, Jason X.-J. Yuan, Optimization of isolated perfused/ventilated mouse lung to study hypoxic pulmonary vasoconstriction. Pulmonary circulation. ,vol. 3, pp. 396- 405 ,(2013) , 10.4103/2045-8932.114776
AH Aldosari, Marco Petasecca, A Espinoza, Matthew Newall, I Fuduli, C Porumb, Sami Alshaikh, ZA Alrowaili, Michael Weaver, P Metcalfe, M Carolan, MLF Lerch, V Perevertaylo, AB Rosenfeld, None, A two dimensional silicon detectors array for quality assurance in stereotactic radiotherapy: MagicPlate‐512 Medical Physics. ,vol. 41, pp. 091707- ,(2014) , 10.1118/1.4892384
A. Bocci, M.A. Cortés-Giraldo, M.I. Gallardo, J.M. Espino, R. Arráns, M.A.G. Alvarez, Z. Abou-Haïdar, J.M. Quesada, A. Pérez Vega-Leal, F.J. Pérez Nieto, Silicon strip detector for a novel 2D dosimetric method for radiotherapy treatment verification Nuclear Instruments & Methods in Physics Research Section A-accelerators Spectrometers Detectors and Associated Equipment. ,vol. 673, pp. 98- 106 ,(2012) , 10.1016/J.NIMA.2012.01.018
I Fuduli, C Porumb, A A Espinoza, A H Aldosari, M Carolan, M L F Lerch, P Metcalfe, A B Rosenfeld, M Petasecca, A comparative analysis of multichannel data acquisition systems for quality assurance in external beam radiation therapy Journal of Instrumentation. ,vol. 9, pp. 1- ,(2014) , 10.1088/1748-0221/9/06/T06003
I Rosenberg, Radiation Oncology Physics: A Handbook for Teachers and Students British Journal of Cancer. ,vol. 98, pp. 1020- 1020 ,(2008) , 10.1038/SJ.BJC.6604224
Ashish R. Pinnapureddy, Cherie Stayner, John McEwan, Olivia Baddeley, John Forman, Michael R. Eccles, Large animal models of rare genetic disorders: sheep as phenotypically relevant models of human genetic disease Orphanet Journal of Rare Diseases. ,vol. 10, pp. 107- 107 ,(2015) , 10.1186/S13023-015-0327-5
Martin J Butson, Peter K.N Yu, Tsang Cheung, Peter Metcalfe, Radiochromic film for medical radiation dosimetry Materials Science & Engineering R-reports. ,vol. 41, pp. 61- 120 ,(2003) , 10.1016/S0927-796X(03)00034-2
Valeria Casanova Borca, Massimo Pasquino, Giuliana Russo, Pierangelo Grosso, Domenico Cante, Piera Sciacero, Giuseppe Girelli, Maria Rosa La Porta, Santi Tofani, Dosimetric characterization and use of GAFCHROMIC EBT3 film for IMRT dose verification. Journal of Applied Clinical Medical Physics. ,vol. 14, pp. 158- 171 ,(2013) , 10.1120/JACMP.V14I2.4111