Notch signaling in prostate cancer: A moving target

作者: Filipe L. F. Carvalho , Brian W. Simons , Charles G. Eberhart , David M. Berman

DOI: 10.1002/PROS.22811

关键词:

摘要: INTRODUCTION By regulating cell fate, proliferation, and survival, Notch pathway signaling provides critical input into differentiation, organization, function of multiple tissues. is also becoming an increasingly recognized feature in malignancy, including prostate cancer, where it may play oncogenic or tumor suppressive roles.

参考文章(105)
Farah A. Falix, Daniël C. Aronson, Wouter H. Lamers, Ingrid C. Gaemers, Possible roles of DLK1 in the Notch pathway during development and disease Biochimica et Biophysica Acta. ,vol. 1822, pp. 988- 995 ,(2012) , 10.1016/J.BBADIS.2012.02.003
Chamelli Jhappan, Cheryl Stahle, Michael Wolff, Glenn Merlino, Ira Pastan, An Epidermal Growth Factor Receptor Promoter Construct Selectively Expresses in the Thymus and Spleen of Transgenic Mice Cellular Immunology. ,vol. 149, pp. 99- 106 ,(1993) , 10.1006/CIMM.1993.1139
Jun Konishi, Keiko S. Kawaguchi, Huan Vo, Nobuhiro Haruki, Adriana Gonzalez, David P. Carbone, Thao P. Dang, γ-Secretase Inhibitor Prevents Notch3 Activation and Reduces Proliferation in Human Lung Cancers Cancer Research. ,vol. 67, pp. 8051- 8057 ,(2007) , 10.1158/0008-5472.CAN-07-1022
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga, Jules Meijerink, Iannis Aifantis, Giuseppe Basso, Carlos Cordon-Cardo, Walden Ai, Adolfo Ferrando, γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia Nature Medicine. ,vol. 15, pp. 50- 58 ,(2009) , 10.1038/NM.1900
Rune Kvåle, Bjørn Møller, Rolf Wahlqvist, Sophie D Fosså, Aasmund Berner, Christer Busch, Anne E Kyrdalen, Aud Svindland, Trond Viset, Ole J Halvorsen, None, Concordance between Gleason scores of needle biopsies and radical prostatectomy specimens : a population-based study BJUI. ,vol. 103, pp. 1647- 1654 ,(2009) , 10.1111/J.1464-410X.2008.08255.X
K Pandya, K Meeke, A G Clementz, A Rogowski, J Roberts, L Miele, K S Albain, C Osipo, Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence British Journal of Cancer. ,vol. 105, pp. 796- 806 ,(2011) , 10.1038/BJC.2011.321
Irene Noguera-Troise, Christopher Daly, Nicholas J. Papadopoulos, Sandra Coetzee, Pat Boland, Nicholas W. Gale, Hsin Chieh Lin, George D. Yancopoulos, Gavin Thurston, Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis Nature. ,vol. 444, pp. 1032- 1037 ,(2006) , 10.1038/NATURE05355
C Osipo, P Patel, P Rizzo, A G Clementz, L Hao, T E Golde, L Miele, ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor. Oncogene. ,vol. 27, pp. 5019- 5032 ,(2008) , 10.1038/ONC.2008.149
Nadine T Gaisa, Trevor A Graham, Stuart AC McDonald, Richard Poulsom, Axel Heidenreich, Gerhard Jakse, Ruth Knuechel, Nicholas A Wright, Clonal architecture of human prostatic epithelium in benign and malignant conditions The Journal of Pathology. ,vol. 225, pp. 172- 180 ,(2011) , 10.1002/PATH.2959
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris IV, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster, Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia Science. ,vol. 306, pp. 269- 271 ,(2004) , 10.1126/SCIENCE.1102160