Efficacy of pneumococcal conjugate vaccines in large scale field trials.

作者: HENRY R. SHINEFIELD , STEVE BLACK

DOI: 10.1097/00006454-200004000-00036

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摘要: AbstractBackground.Each yearStreptococcus pneumoniaecauses ˜1.2 million deaths worldwide from pneumonia. In the United StatesS. pneumoniaeis estimated to cause 500 000 cases of pneumonia and 7 episodes acute otitis media annually.Conjugate vaccines.The current pneumococcal polysaccharide

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