Prevalence of influenza A (H1N1) seropositivity in unvaccinated healthcare workers in Scotland at the height of the global pandemic.

作者: Kate Smith , Pamela Warner , Linda J. Williams , Walt E. Adamson , S. Vittal Katikireddi

DOI: 10.1155/2011/407505

关键词:

摘要: Background. We set out to identify the level of previous exposure influenza A (H1N1) in unvaccinated healthcare workers (HCWs) at peak pandemic outbreak UK, with control samples collected prior outbreak. Methods. Cross-sectional study (seroprevalence assessed before and peak, questionnaire data outbreak) HCWs Scotland. Results. The prevalence seropositivity 493 was 10.3%, which higher than prepandemic by 3.7 percentage points (95% CI 0.3% 7.3%, P = 0.048). Seropositivity rates for frontline nonfrontline were similar. Conclusion. At only 10.3% seropositive (H1N1), so great majority still susceptible infection introduction vaccination programme. Few studies have reported on seroprevalence asymptomatic participants, our findings may relevance wider population.

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