Gender-Specific Differences in Surgical Site Infections: An Analysis of 438,050 Surgical Procedures from the German National Nosocomial Infections Surveillance System.

作者: Corinna Langelotz , Carolin Mueller-Rau , Stoil Terziyski , Beate Rau , Alexander Krannich

DOI: 10.1159/000362100

关键词:

摘要: Background: Surgical site infections (SSI) are among the most frequent healthcare-associated infections. They impose a substantial burden with increased morbidity and exceeding healthcare costs. Risk factors such as age, diabetes, smoking status commonly accounted for in literature, but few studies address gender differences. Methods: Data from German Nosocomial Infections Surveillance System (Krankenhaus-Infektions-Surveillance-System (KISS)) 2005 to 2010 were analysed cardiac, vascular, visceral, orthopaedic surgery, total of 438,050 surgical procedures 8,639 SSI. Rates SSI isolated pathogens gender. Results: Women had lower rate (SSI/100 procedures) abdominal surgery than men (2.92 vs. 4.37; p Staphylococcus aureus Pseudomonas aeruginosa, which more women (both = 0.007), while coagulase-negative staphylococci occurred often (18.8 14.0%; Conclusion: Gender differences exist procedure-specific. The underlying mechanisms need be further elucidated so that targeted measures prevention can developed.

参考文章(16)
P. Gastmeier, M. Behnke, A.-C. Breier, B. Piening, F. Schwab, M. Dettenkofer, C. Geffers, Nosokomiale Infektionsraten: Messen und Vergleichen Bundesgesundheitsblatt-gesundheitsforschung-gesundheitsschutz. ,vol. 55, pp. 1363- 1369 ,(2012) , 10.1007/S00103-012-1551-Y
Michael Behnke, Sonja Hansen, Rasmus Leistner, Luis Alberto Peña Diaz, Alexander Gropmann, Dorit Sohr, Petra Gastmeier, Brar Piening, Nosocomial infection and antibiotic use: a second national prevalence study in Germany. Deutsches Arzteblatt International. ,vol. 110, pp. 627- 633 ,(2013) , 10.3238/ARZTEBL.2013.0627
A. Nicchia, F. Paradiso, C. Russo, P. Saturnino, C. Serio, Surveillance of surgical site infection European Journal of Hospital Pharmacy. ,vol. 19, pp. 174- 174 ,(2012) , 10.1136/EJHPHARM-2012-000074.235
C.D. Owens, K. Stoessel, Surgical site infections: epidemiology, microbiology and prevention Journal of Hospital Infection. ,vol. 70, pp. 3- 10 ,(2008) , 10.1016/S0195-6701(08)60017-1
Nauder Faraday, Peter Rock, Elaina E. Lin, Trish M. Perl, Karen Carroll, Tracey Stierer, Polly Robarts, Angela McFillin, Tracy Ross, Ashish S. Shah, Lee H. Riley, Rafael J. Tamargo, James H. Black, Elena Blasco-Colmenares, Eliseo Guallar, Past history of skin infection and risk of surgical site infection after elective surgery. Annals of Surgery. ,vol. 257, pp. 150- 154 ,(2013) , 10.1097/SLA.0B013E3182588ABF
C Gibbons, J Bruce, J Carpenter, AP Wilson, J Wilson, A Pearson, DL Lamping, ZH Krukowski, BC Reeves, Identification of risk factors by systematic review and development of risk-adjusted models for surgical site infection. Health Technology Assessment. ,vol. 15, pp. 1- 156 ,(2011) , 10.3310/HTA15300
C. Brandt, D. Sohr, M. Behnke, F. Daschner, H. Rüden, P. Gastmeier, Reduction of surgical site infection rates associated with active surveillance. Infection Control and Hospital Epidemiology. ,vol. 27, pp. 1347- 1351 ,(2006) , 10.1086/509843
John A. Weigelt, Benjamin A. Lipsky, Ying P. Tabak, Karen G. Derby, Myoung Kim, Vikas Gupta, Surgical site infections: Causative pathogens and associated outcomes American Journal of Infection Control. ,vol. 38, pp. 112- 120 ,(2010) , 10.1016/J.AJIC.2009.06.010
Bruna Romana-Souza, Thatiana L. Assis de Brito, Gabriela R. Pereira, Andréa Monte-Alto-Costa, Gonadal hormones differently modulate cutaneous wound healing of chronically stressed mice. Brain Behavior and Immunity. ,vol. 36, pp. 101- 110 ,(2014) , 10.1016/J.BBI.2013.10.015
Erin E. McClelland, Jennifer M. Smith, Gender Specific Differences in the Immune Response to Infection Archivum Immunologiae Et Therapiae Experimentalis. ,vol. 59, pp. 203- 213 ,(2011) , 10.1007/S00005-011-0124-3