Aberrations of chromosome 19: Do they characterize a subtype of benign thyroid adenomas?

作者: Gazanfer Belge , Brita Thode , Jörn Bullerdiek , Sabine Bartnitzke

DOI: 10.1016/0165-4608(92)90227-Y

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摘要: Abstract We describe the cytogenetic findings in two benign thyroid hyperplasias with aberrations of chromosome 19. In first patient, four nodules showed identical translocations involving 19 and 22: 46,XX,der(19)t(19;?)(q13;?),der(22)t(22;?)(q12;?), remaining had an apparently normal karyotype. Two from a second patient were karyotyped. One karyotype 46,XX,t(1;19)(p35–36.1;q13) other From these results as well those reported previously, we can conclude that structural changes characterize subgroup adenomas, hyperplasias, or both.

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