Thyroid nodular hyperplasia: chromosomal studies in 14 cases.
作者： Lúcia Roque , Paula Gomes , Cecília Correia , Paula Soares , Jorge Soares
DOI: 10.1016/0165-4608(93)90108-X
关键词: Thyroid nodular 、 Hyperplasia 、 Internal medicine 、 Endocrinology 、 Thyroid 、 Karyotype 、 Biology 、 Pathogenesis 、 Pathology
摘要: Abstract Cytogenetic study of 14 thyroid nodular hyperplasias revealed a hyperdiploid karyotype in two cases (14%) and normal chromosomal complement the remaining cases. Some numerical alterations found were identical to ones considered characteristic subset adenomas (+;5, +;7, +;9, +;12, +;14, +;16). Our findings suggest that cytogenetic events involved pathogenesis hyperplastic lesions benign tumors may be closely related, which supports hypothesis biologic “continuum” between these types lesions.
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