Systems Biology and Systems Medicine

摘要: Abstract Systems medicine and the digital revolution are together transforming healthcare to a proactive P4 that is predictive, preventive, personalized participatory. biology—holistic, global integrative in approach—has given rise systems medicine, approach health disease. promises 1) provide deep insights into disease mechanisms, 2) make blood diagnostic window for viewing individual, 3) stratify complex diseases their distinct subtypes an impedance match against proper drugs, 4) new approaches drug target discovery 5) generate metrics assessing wellness. clinical face of has two major objectives: quantize wellness demystify Patients consumers will be driver realization through participation medically oriented social networks directed at improving own healthcare. striking implications society—including ability turn around ever-escalating costs The challenge bringing patients two-fold: first, inventing strategies technologies enable second, dealing with impact on key ethical, social, legal, regulatory, economic issues. Managing societal problems pose most significant challenges. Strategic partnerships variety types necessary bring patients.