Formulation of Biotech Products, Including Biopharmaceutical Considerations

作者: Daan J. A. Crommelin

DOI: 10.1007/978-1-4614-6486-0_4

关键词:

摘要: This chapter deals with formulation aspects of pharmaceutical proteins. Both technological questions and biopharmaceutical issues such as the choice delivery systems, route administration, possibilities for target site-specific proteins are considered.

参考文章(194)
Jeremy K. Nicholson, Ian D. Wilson, Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism Nature Reviews Drug Discovery. ,vol. 2, pp. 668- 676 ,(2003) , 10.1038/NRD1157
Randy L. Jirtle, Michael K. Skinner, Environmental epigenomics and disease susceptibility Nature Reviews Genetics. ,vol. 8, pp. 253- 262 ,(2007) , 10.1038/NRG2045
Erik Björk, Peter Edman, Characterization of degradable starch microspheres as a nasal delivery system for drugs International Journal of Pharmaceutics. ,vol. 62, pp. 187- 192 ,(1990) , 10.1016/0378-5173(90)90232-S
Markus R. Wenk, The emerging field of lipidomics Nature Reviews Drug Discovery. ,vol. 4, pp. 594- 610 ,(2005) , 10.1038/NRD1776
Munir Pirmohamed, Pharmacogenetics: past, present and future Drug Discovery Today. ,vol. 16, pp. 852- 861 ,(2011) , 10.1016/J.DRUDIS.2011.08.006
Saran Kumar, Hing Char, Sunil Patel, David Piemontese, A.Waseem Malick, Khurshid Iqbal, Eric Neugroschel, Charan R. Behl, In vivo transdermal iontophoretic delivery of growth hormone releasing factor GRF (1–44) in hairless guinea pigs Journal of Controlled Release. ,vol. 18, pp. 213- 220 ,(1992) , 10.1016/0168-3659(92)90167-P
Pierre A.M. Peeters, Gert Storm, Daan J.A. Crommelin, Immunoliposomes in vivo: state of the art Advanced Drug Delivery Reviews. ,vol. 1, pp. 249- 266 ,(1988) , 10.1016/0169-409X(88)90021-X
Alisa Opar, 'Pharmers' hope for first plant drug harvest Nature Reviews Drug Discovery. ,vol. 10, pp. 81- 82 ,(2011) , 10.1038/NRD3369
Anna Portela, Manel Esteller, Epigenetic modifications and human disease Nature Biotechnology. ,vol. 28, pp. 1057- 1068 ,(2010) , 10.1038/NBT.1685
G.F. Maberly, G.A. Wait, J.A. Kilpatrick, E.G. Loten, K.R. Gain, R.D.H. Stewart, C.J. Eastman, Evidence for insulin degradation by muscle and fat tissue in an insulin resistant diabetic patient Diabetologia. ,vol. 23, pp. 333- 336 ,(1982) , 10.1007/BF00253740