Myocardial infarction risk in relation to zinc concentration in toenails

摘要: Zn is an essential mineral. The role of in atherosclerosis not clear. Epidemiological studies, which have reported contradictory results, are limited by the use serum levels as a marker intake. We assessed association toenail Zn, integrates dietary intake over 3 to 12 months, with risk first myocardial infarction. Toenail concentrations were determined neutron activation analysis European multi-centre case ‐ control study on antioxidants, infarction and breast cancer. This ‐control included 684 cases 724 controls from eight countries Israel. (adjusted for age centre) positively associated age, a-tocopherol Se, but additional variables or classical factors CHD. Average was 106·0 mg/kg (95 % CI 103·1, 108·9) 107·5 104·5, 110·7). After controlling cardiovascular centre, adjusted odds ratios quintiles 2 5 respect quintile 0·97 0·59, 1·58), 1·15 0·72, 1·85), 0·91 0·56, 1·50), 0·85 0·52, 1·39). P trend 0·45. In conclusion (reflecting long-term intake) significantly acute Case– studies: Heavy metals: Zinc: Myocardial infarction: Neutron