Clinical experiences on aggressive angiomyxoma in China (report of 93 cases)

摘要: Objective: To discuss the clinical experiences of aggressive angiomyxoma (AAM) by summarizing information patients with this disease in China. Methods: Chinese articles concerning AAM were retrospectively reviewed and analyzed. Results: A total 93 cases 44 well-documented had been reported, among which 11 male 82 female, a to female ratio 1:7.45. The age females varied from 14 55 years (mean [SD], 37.17 [10.39] years; median, 38.5 years), whereas that males ranged 15 65 44.75 [17.61] was significantly higher than (t = 2.082, P 0.041). most common sites perineum scrotum males. None could be accurately diagnosed as preoperatively. mean minimum diameter tumors 4.62 (3.51) cm, maximum 9.12 (8.23) cm. All specimens showed typical pathological features reported previously. Immunohistochemistry indicated tended strongly positive for vimentin, smooth-muscle actin, CD34 but mostly negative S-100 CD68. duration postoperative follow-up 3 96 months 28.5 [18.86] months; 9.5 months) cases, recurrence rate 31.82%. Conclusions: Aggressive must considered differential diagnosis any an asymptomatic perineal mass. complete margin-free excision should achieved avoid recurrence. Long-term is quite necessary because high local