A histopathological tool for quantification of biomarkers with sub-cellular resolution

摘要: Quantification of protein expression levels with sub-cellular resolution in histological images is important many applications, such as biomarker discovery and cancer treatment. The use computer-assisted analysis digital tissue samples can be an alternative to the more labour-intensive manual identification classification, numerous are methods that have been developed quantify images, offering both objectivity reproducibility. problem these they not made accessible for pathology community when are, users often experience a trade-off between simplicity flexibility complex research applications. This paper presents software tool used extracting quantifying data from whole-slide (WSIs) using computerised image analysis. It detection, classification quantification structures, nuclei, cytopla...