Alcohol Intoxication and Withdrawal: The Role of Nitric Oxide
作者： Michael L. Adams , Theodore J. Cicero
DOI: 10.1016/S0741-8329(97)00185-7
关键词:
摘要: Nitric oxide is an important messenger in the central nervous system and several types of evidence suggest that it mediates various alcohol effects. Treatment with a nitric synthase inhibitor enhances acute depressant or anesthetic effect decreases some stimulatory effects withdrawal after chronic treatment. Conversely, treatment donor inhibits alcohol, blocks on anesthesia, severity signs. These results indicate changes synthesis mediate aspects intoxication systems represent therapeutic target for development agents to treat alcoholism intoxication.
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