作者: Fernando G. Correa , Leyre Mestre , Fabián Docagne , José Borrell , Carmen Guaza
DOI: 10.1016/S0083-6729(09)81009-1
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摘要: Over the last decade, endocannabinoid system (ECS) has emerged as a potential target for multiple sclerosis (MS) management. A growing amount of evidence suggests that cannabinoids may be neuroprotective during CNS inflammation. Advances in understanding physiology and pharmacology ECS have potentiated interest several components this useful biological targets disease Alterations been recently implicated number neuroinflammatory neurodegenerative conditions, so pharmacological modulation cannabinoid (CB) receptors and/or enzymes controlling synthesis, transport, degradation these lipid mediators is considered an option to treat neurological diseases. This chapter focuses on our current function anandamide (AEA), its therapeutic implications, well description effects neuroimmune modulation.