Quinolonecarboxylic acid derivatives or salts thereof

作者: Junichi Mitsuyama , Kazuya Hayashi , Tetsumi Yamakawa , Hiroyo Kawafuchi , Tokunori Kito

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摘要: Novel quinolonecarboxylic acid derivatives represented by general formula (1) which have potent antibacterial effects on gram-positive bacteria, in particular, Propionibacterium acnes, wherein R1 represents hydrogen or a carboxyl-protective group; R2 optionally substituted cycloalkyl; R3 hydrogen, halogeno, alkyl, alkoxy alkylthio, protected hydroxy amino, nitro; R4 alkyl alkoxy; Z alkenyl, cycloalkyl, alkoxy, amino pyridin-4-yl pyridin-3-yl having one more substituents selected from among and amino.

参考文章(20)
Munirathnam K. Chaguturu, John A. Dixson, Clinton J. Peake, John W. Buser, Partha S. Ray, N. Henrie Ii Robert, Walter H. Yeager, Thomas G. Cullen, Albert C. Lew, James J. Fiordeliso, Ian R. Silverman, Insecticidal substituted-2,4-diaminoquinazolines. ,(1994)
Joel D. Enas, Anat Biegon, Chester A. Mathis, Scott E. Taylor, Substituted 6-nitroquipazines, methods of preparation, and methods of use ,(1992)
Toshio Hatada, Shigeo Ohashi, Shinji Tanaka, Cooling unit for electronic equipment ,(1996)
Larry J. Black, George J. Cullinan, Methods for inhibiting bone loss ,(1996)
William Adcock, S. Q. A. Rizvi, William Kitching, Alan J. Smith, Group IVb metalloidal and mercury substituent effects in the naphthalene system by fluorine-19 nuclear magnetic resonance Journal of the American Chemical Society. ,vol. 94, pp. 369- 374 ,(1972) , 10.1021/JA00757A010
Beno[icaron]t Joseph, Béatrice Malpel, Jean-Yves Mérour, 1-(Phenylsulfonyl)indol-2-yl Triflate: A Versatile Reagent for the Synthesis of 2-Substituted Indoles Synthetic Communications. ,vol. 26, pp. 3289- 3295 ,(1996) , 10.1080/00397919608004639
Ronald Eugene White, Thomas Prosser Demuth, Antimicrobial 5-hydrazino-quinolone derivatives ,(1993)
Rudolf Then, Henri Stalder, Raffaello Masciadri, Philippe Guerry, Synese Jolidon, Novel benzyl pyrimidines ,(1995)