Heterogeneity in the Response to Antiretroviral Therapy

摘要: The dynamics of viral suppression and the quality immune reconstitution after initiation potent antiretroviral therapy may vary considerably from person to person. heterogeneity response reflects a summation host factors. Thus, analysis different responses provide clues on biology replication under constrains drug pressure, or critical aspects mechanisms CD4 T-cell depletion. On clinical side, decisions treatment switch discontinuation might need take into account unexpected benefits suboptimal therapy. There is also an urgent for understanding phenomenon progressive immunosuppression exhausting all available combinations.