Pharmacological characterization and autoradiographic localization of dopamine D1 receptors in the human umbilical artery.

作者: José Antonio Ferreira-de-Almeida , Luis Pereira-Leite , Carlo Cavallotti , Alberto Ricci , Francesco Amenta

DOI: 10.1016/0014-2999(93)90955-H

关键词:

摘要: Combined in vitro radioreceptor binding and autoradiographic techniques with [3H]SCH 23390 as a ligand were used to analyze the pharmacological profile anatomical localization of dopamine D1 receptor sites sections human umbilical artery. The was bound artery manner consistent labelling receptors. These receptors, which show fetal-to-maternal gradient highest concentration near placenta, are located within smooth muscle layer above findings suggest that endogenous may be involved control tone through interaction

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