Characterization of the receptor mediating contraction of human umbilical artery by 5-hydroxytryptamine.
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DOI: 10.1111/J.1476-5381.1985.TB17370.X
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摘要: The 5-hydroxytryptamine (5-HT) receptor in human umbilical artery was found to be similar that rabbit aorta. pD2 7.45, pA2 for methysergide 8.63 and phentolamine 6.21. Noradrenaline gave only very weak contractions at non-physiological concentrations. Amidephrine xylazine did not contract artery. It is concluded there no significant population of functional alpha-adrenoceptors this vessel. implications these findings are discussed relation the control circulation.
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